I dunno... I think the lower fi samplers definitely have a place that isn't covered by kontakt and a moogerfoger. (not that I ever used kontakt or ever owned a moogerfooger)
There's a few people on the emax list working towards making the emax (and if that happens, next step will quite likely EII, which has similar comms) a lot more pc integrated. if we can get it to work, you'll be able to boot the emax to a blank program, and then blast sample banks (assembled in a program on the pc, using wave files off the hdd) back and forth between the emax and the computer using the 500k RS422 link plugged into a PC USB port.
Also, I've modded my emax to have the SCSI option, and have a flash card reader and some CF cards that have come in the mail, just waiting for me to pick up and install when I get a chance, so I'm almost already over the whole floppy disk reliance issue. Then if we can make the fast sample transfer work, an emax will be a really amazing piece of gear.
This kind of functionality already exists for some of the top end late model samplers too (though using SCSI) maybe most of these people you mentioned who brought and then flipped the high end samplers didn't try to get this side of things working? It's not so simple to do in these days of non-scsi laptops everywhere.... I'm still hunting about for a decent SCSI adapter for my laptop so I can integrate my A5000 and E64 properly.
if anything, with the advent of ableton live, and the way it's grown with sample warping features, and now how all other daws are adding features to match, I'm beginning to think the least relevant form of sampler now is the vsti sampler. I grabbed short circuit off the net about 6 months ago, installed it and had a bit of a play. It's meant to be one of the best and easiest samplers out there for working with samples, rather than just playing back big libraries...... and then in the last 6 months I haven't had a SINGLE time, when dealing with wave files in my computer, that it wasn't faster and simpler just to chop up and warp stuff in ableton, or arrange chunks of audio in cubase.